Overview

Cell and gene therapy is continuously advancing. This half-day event will provide an update on the rapidly evolving landscape of cell and gene therapies, cover the current challenges in viral vector manufacturing, as well as how to advance the viral vector manufacturing capability in the UK and discuss the challenges encountered in the scaled up expansion of stem cells and ways to overcome these limitations.

Open to all, this event will give the opportunity to listeners to hear from experts in the cell and gene therapy sector about the advancements and limitations of such medicinal products. A selection of talks will be delivered by experts from relevant industry and academia. There are also opportunities for early career researchers (PhDs and postdoctoral researchers) to present their work in short talks and compete for the Early Career Researcher Prize.

Speakers

• Peter Jones, Oxford Biomedica
• Damian Marshall, Cell and Gene Therapy Catapult
• Karen Coopman, Loughborough University
• Sharon Brownlow, Cell and Gene Therapy Catapult
• Angela Imere, University of Manchester: Tissue engineering the tendon synovial sheath for anti-adhesive properties
• Angharad Evans, Loughborough University: Optimising the culture of viral production cell lines for improved lentiviral manufacture
• Hannah Donnelly, University of Glasgow: Bioengineering the bone marrow stem cell niche in vitro
• Oana Dobre, University of Glasgow: Hybrid 3D Laminin hydrogels for stem cells control
• Martina Miotto, CellulaREvolution, Newcastle: Applying continuous bioprocessing to cell manufacturing
• Fritz de la Raga, Aston University: Development of a bioprocess for the expansion and differentiation of IPSCs

The material presented has not been peer-reviewed. Any opinions are the presenter’s own and do not necessarily represent those of IChemE or the Biochemical Engineering Special Interest Group. The information is given in good faith but without any liability on the part of IChemE.

Agenda

• 09:30—09:35 - Welcome and Introduction
• 09:35—10:00 - Damian Marshall, Cell and Gene Therapy Catapult: The Emergence, The Challenge and The Future of Gene Therapies
• 10:00—10:25 - Sharon Brownlow, Cell and Gene Therapy Catapult, Advancing UK Vector Manufacturing Capability
• 10:25—11:10 - 3 x Early career researcher's talks
• 11:10—11:20 - Break
• 11:20—12:05 - 3 x Early career researcher's talks
• 12:05—12:30 - Peter Jones, Oxford Biomedica, Gene Therapy: promises and challenges
• 12:30—12:55 - Karen Coopman, Loughborough University, Challenges in Microcarrier Based Culture and How To Overcome Them 
• 12:55—13:00 - Closing remarks, prize announcement and wrap up